Have you tried the Blender.Org help forum? Aside from a computer on the edge of going belly up and thus messing up Blender [and that did happen to me once] you need to take into account that Python is not automatically installed along with Blender. These are separate installations and both have unique build numbers. I once had an old build of Python and the newest version of Blender and the two did not like one another.
My point is that the problem could be any number of things. Yeah, we can give it a try guessing what is happening with your computer and Blender, but you should probably ask the people at Blender.org's forum.
Hmmm . . . you might also look at some freeware hardware-diagnostic-tools and run them on your computer to see if everything important is one hundred percent -- er -- healthy. If you have any suspicion at all that your computer's motherboard or your hard drive is faltering then you have waaaaaay bigger trouble staring you in the face than just a stubborn Blender build.
Eternal student in search of knowledge. But will settle for the occasional epiphany.