Nice game, although i suck at it. I think everyone died. Great aesthetics - city looks really nice, and the crate, plus the disintegration effect is pretty awesome. You could do with finding some sounds for it, and by offering a restart at the end, instead of having to load the whole thing again.
I found the mouse not sensitive enough, but this may well be related to Windows Desktop settings, screen resolution and that, so i don't know what you can do about that. Perhaps you could have a mouse sensitivity setting text file.
BTW, looking at your screenshot, you may want to look at where the laser beam is in the draw order ( ie what image number is used), zwrite etc. It seems the laser is drawn correctly relative to the crates, but is not transparent over the background.