alot of sites look good on 640x480, Macromedia's for example is very good at all resolutions - very well designed site, though i mean wouldn't be good for business if the leading authority on web design products was unreadable on some resolutions and colour rates.
the sits been designed for a 1024x768 desktop in mind, i dropped to 800x600 to check out how it would look and it seems totally too cramped ... not the menu as thats only slightly larger but the actual main body.
Which could actually be fixxed by making the topright menu have another menu below with all of the left hand colomn stuff on it (as thats all just simply links anyway to the forum/newsletter/etc... all TGC stuff anyways)
And the left hand one doesn't really have enough information to warrent the space on the side, you could quite easily make a lower frame where you can put the "featured" "advert" "dtotd" "recent new stories headers" ... those headers could then lead to a java popup of the full story, alot of sites do this to save space and the need for pictures or lengthy descriptions.
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don't get me wrong i like the site, but it really isn't optimised for anyone on a lower res monitor ... like what they have in schools that most can't alter as all access to system areas is oftenly denied.
don't agree with how 8truths put it though.