I'm looking into speech recognition at work - operators using microscopes, going back and forth to a PC, so we want them to just speak the information, and it'll parse it and store it in a database. Will probably save a lot of time.
There was a blind guy on the forum, coding in DBPro while blind, pretty scary stuff - no idea how that went though. I did make a little example for him - a forest, with a little river etc, worked out pretty well. I think I ended up adding to the 3D sound in DBPro, using a multiplier thing so that the range of a sound can be controlled. I'll see if I can find it and post it up here - it was very cool, like the start of a text adventure.
There's actually a strong market for these things, and you'd be amazed how much support you can muster for a game that benefits disabled people.
Health, Ammo, and bacon and eggs!