Using a template from 1076, I'm able to get both debug and release compiling and running (mind you it's just a simple "Hello World" program).
I'm no wizard with Visual Studio so I'll list everything I did to get it to work.
1. Make a copy of the template_vs10 folder and paste it somewhere you're going to remember - this is project we're going to be working with.
2. Open the solution (if it wants to convert it, let it).
3. In the solution explorer, click on the project and go into the properties.
4. Click on Configuration -> VC++ directories tab and link the "Include" (IDE - common - include), "Library" (remember to select the vs2010 version) and "Source" (IDE-platforms-windows) files to the corresponding AppGameKit files.
5. In C/C++ general, you'll see "Additional Include Directories". Change this to an absolute path i.e, go browsing for the Include (same one as in step 4)
6. In Linker->General, find "Additional Library Directories" and change that to an absolute path i.e, go browsing for the Library->VS2010->Debug folder (same as in step 4).
7. Click Ok.
I'm pretty sure that's everything I did but I can't guarantee that'll result in successful compilation in Debug mode (I've only tried it on one project). Good luck!
Edit-Just went through my steps with a fresh copy of the template_vs10 folder and got both debug and release compiling and running.
One thing that may not be necessary is linking to the "Source" folder in step 4 as I didn't do it this time and everything still ran but I'll leave it in there anyway, just in case.