Quote: "1. Is it compatable with major video card brands? It uses Nvidia Physx ("harness the awesome capabilities of the NVIDIA PhysX™")"
It should be compatible with other brands if you install PhysX driver (end-users will also need to install it). Most new Nvidia drivers come bundled with PhysX driver.
Quote: "2. If not, then is there a non-Physx mode?"
There's no such thing. As Bigglesworth suggested, look into DarkDynamix it's essentially a pimped up version of DarkPhysics which does not require separate PhysX installation (all physx dlls are to be distributed alongside your executable). It is also faster and less bugged.
Quote: "I am also looking at Enhanced Animation. Does it have a "rag-doll" funtion? It didn't say on the fact sheet....."
Enhanced Animations has nothing to do with physics. It allows you to extract, modify and apply animation data to separate limbs (e.g. shoot gun with upper part while lower part of body is cycling through running animation).
Intel Core2Duo 2.2GHZ, 2GB, GeForce 8600M GT 1280MB, Windows Vista Ultimate SP2, PureBasic 4.61 + DarkGDK 2.0