Quote: "Last I read the CSG feature was not going to be a "real time" feature, that you wouldn't be able to use it to blow holes in walls or doors in-game. Am I wrong?"
For low-poly geometry, CSG can probably be done in realtime.
Quote: "Also, the Nodetree/Portals, don't these require some precalc? If so, how long loading times should we expect?"
You'll need to ask Mike on that, but at the UK convention it all seemed fairly quick. With a lot of things the idea is that you will be able to manipulate the object then save it out as DBO.
Quote: "You forgot Bugs! err... I mean Bugfixes."
No word on that yet, but obviously they are a major part of it.