I personally think it depends on what type of game your making.
Now this doesn't come from firsthand animation knowlage, however, if you look at many different games they all have different styles.
Many games, I would say, go with what WOLF said, they exaggerate movements so that they are clearly visable. I think one way to help is to ensure the entire body moves whenever a motion is made. If you also have an animation of the model standing, then he will always be moving. Because in real life your head doesn't remain perfectly fixed all the time, it sways a tiny bit and your arms move a little.
Other than that your on your own.
"Damn had to remake account!" direct quotation from previous account.