Oh god...
I'll be helpful now:
1. Many people
hate Comic Sans, including me. Look into Verdana or Arial.
2. Make the Marquee (spelling?) background the same as the background...more on the colour in a second.
3. Colour: That's a nice blue, and an ok grey - they go together if used correctly, but that wouldn't look bad. However, red does not go with blue...and not well with grey. Red goes with black better.
To show you an example of colours:
http://pulse.dbspot.com and
http://pulse.dbspot.com/AQA which both have quite nice colour schemes.
I think that will be a start, sorry if that seems harsh
N30F15H