It depends I think, on how you position the sprites/pastes. I would tend to allow a few pixels as a border, then have the tiles more 3D, then offset it to the middle of the diamond. Something like this...
Then taller tiles might have double the height, but always with the diamond at the bottom. As long as your diamonds slot together you can do it however you like, I tend to have the top and bottom of the diamond 4 pixels wide, for the left and right sides of the next row of tiles to meet up with.

I got a fever, and the only prescription, is more memes.
