Erm, I can see why people think it's weird because it was a program designed for young girls, which would seem pretty creepy. I mean, particularly when you find the media obsesses with things like pedophilia, so it probably helps make it creepy. But as a teenager I enjoyed the Powerpuff Girls because I enjoyed it as a cartoon. But I think today if somebody said, "I want to be a kids' TV presenter" people are probably more likely to think that creepy, particularly in light of cases like Jimmy Saville, but some people generally like to entertain kids or like being with kids in a totally non-dodgy way. Likewise, somebody can enjoy kids TV without being a weirdo.
With Bronies, I think it was just simply a case of people discovering they enjoyed something and I am sure there was the novelty of it being My Little Pony and it having the shock factor, which probably made people draw attention to it more. However, there's a lot of series out there that have a big following and things people obsess over. Should the fact I own a DeathNote be any different to somebody with a MLP hat? Or the fact I have a Darth Malgus collectable on my windowsill be any different to somebody with Twilight Sparkle instead?
People cosplay too, people go to Trekkie conventions dressed as Spock and others go to anime conventions - many of which involve cross dressing. People go to gaming conventions dressed as Master Chief. There's a high level of geekery in the world and given MLP attracts a geek crowd it's only natural geeky obsessions would follow.
But I don't think it's weird or creepy, I suspect there are the genuinely creepy, but same applies to any of these kinds of conventions, but you can't judge a population based on the creepy few.