If you use sprites then you can, and offsetting the paste image would do the same thing, problem is that you'd have to figure out each hotspot location, and that's about as time consuming as manually adjusting the positions.
Personally if I was making a load of sprites, I'd make a custom sprite editor that can be used to preview animations, edit sprites, hotspots etc etc. Drawing sprites is time consuming enough, but often it's just figuring out what they need to do that takes the most time. If you made it in DB, you could even render 3D objects as sprites - which you might find very usefull, esp for isometric games.
Van-B

It's c**p being the only coder in the village.