This would be better if (in addition to VS Express) it worked with VS2005 Standard or any of the Non-Express edditions.
VSExpress editions have no built in deployment capability. Here is a link to an Eleven-Step process to deploy even a simple VC++ Express application: http://blogs.msdn.com/nikolad/archive/2005/09/02/running-c-application-built-by-vc-express-on-another-computer.aspx
What does this mean? Even if you buy the full commercial license of DarkGDK at $500, you are stuck with VC++Express and it's inability to create Setup projects for your games.
A third party scripting deployment tool like Inno could possibly be used, but what a bother. At $500, I shouldn't have to use one of those.
Note: This is nothing against theGameCreators or their cool products. This is a Microsoft failing.